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How safe is fructose for persons with or without diabetes?

In this issue of the journal, Livesey and Taylor (1) present a meta-analysis of clinical trials evaluating the effects of fructose intake. They concluded that fructose is safe at doses of <90 g/d and that it may have the added benefit of lowering concentrations of glycated hemoglobin (HbA1c). This meta-analysis is difficult to interpret, because it involves randomized and nonrandomized studies of differing designs, mixed populations (diabetic and non diabetic  lean and obese), different control diets (including some sucrose-based diets that contained fructose), different study durations, and limited endpoints; it also represents an analysis by an industry-sponsored group of a highly selected list of studies

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We revisit an old hypothesis that sugar, particularly excessive fructose intake, has a critical role in the epidemic of cardiorenal disease. The epidemic of cardiorenal disease is characterized by increasing rates of obesity, hypertension, the metabolic syndrome, type 2 diabetes, and kidney disease. This may also explain why certain subgroups, such as African Americans, are particularly prone to disease. Clearly, much more work needs to be done to prove or disprove this hypothesis. Anyway, having a balanced diet often goes along with less pre-packaged processed food with added fructose. But many of us like pre-packaged processed food because it is easier to count what you eat. For people with chronicle diseases, counting food intake is much more simple. But what if we could count homemade food with a mere click of a button? Sounds Science fiction? That’s why we worked hard to develop this sleek, snappy, little app just for you. By scanning your food, even homemade, it will take 1 click to log it, 10 times less clicks than manual input methods to input processed food. So, no excuse, start eating healthy and get rid of fructose without stopping counting your food intake. Visit

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